If there are no symptoms or changes, the FDA recommends breast implants should be screened for a rupture with breast ultrasound or breast MRI 5 6 years after surgery to place the implant, and then every 2 3 years
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Clinical studies with antipyrine and warfarin showed that anastrozole at a 1 mg dose did not significantly inhibit the metabolism of antipyrine and R and S warfarin indicating the co administration of anastrozole with other medicinal products is unlikely to result in clinically significant medicinal product interactions mediated by CYP enzymes